The Heikoff Giant Dome Theater will be closed for upgrades from September 7–October 28. It will reopen on Friday, October 29, with a brand new IMAX® laser digital projection system.
   We’re Open Today
10:00am to 5:00pm

Senior Monday

On the first Monday of every month, seniors can enjoy all the Fleet has to offer!
Seniors 65 and better enjoy a show in the Heikoff Giant Dome Theater and the opportunity to attend an engaging lecture about exciting scientific topics—all at the discounted admission of $10!
Tickets are available through the Fleet website and at the ticket counter. Fleet Members have free access to the Sharp Minds lecture, but will need to use a voucher to enjoy the special film. 

Date: September 6

NO Sharp Minds lecture and movie in September in observance of Labor Day

Date: October 4

Title: Mechanics of Genetic Diseases

Time: 10:30–11:30 a.m. followed by the special screening of TBA.


Most genetic disorders are present from birth and some are quite rare, sometimes affecting only one person in every several thousand or million. Join Dr. Jonatan Matalonga as he shares more about his work on the discovery of new genetic disorders and improving our understanding of those we already know. Using zebrafish, mouse models, patient cells and stem cell technologies, he and is fellow researchers are probing the pathological mechanisms of genetic disorders to address unanswered questions.

Bio: TBA

Please note: Since our Heikoff Dome Theater will be closed for renovation, we will be hosting this event in our Community Forum. Seating will be limited and we encourage you to purchase your tickets online in advance of the event. You can purchase tickets here.

Date: November 1

Title: Our Dynamic Microbiomes and the Brain

Time: 10:30–11:30 a.m. followed by the special screening of The Human Body at noon.

Our lifespans are ever-increasing, but our healthspans are not, leading to long periods of unpleasant and expensive suffering with chronic conditions. Many of these conditions have receantly been linked to the microbiome, via advances in DNA sequencing technology and software to interpret those sequences. We change our microbiomes every day through the foods we eat, the environments we experience, even the people we live and work with. The implications of these changes in the microbiome for our health are just beginning to be understood. And many of the effects are systemic: what happens in the gut doesn’t stay in the gut, and your gut microbiome can affect your liver, your joints, and even your brain. Through the American Gut Project and the Microsetta Initative, the largest crowdsourced and crowdfunded citizen-science project yet conducted, we now know about the microbiomes of many types of people, from the healthiest (student-athletes, centenarians) to the sickest (cancer patients, ICU patients, those with depression, those with C. diff). Amazingly, diet has an especially profound effect on our microbiomes, often outweighing the effects of disease or medications. This raises the prospect of a system for real-time analysis of our microbiomes that helps guide our daily decisions in a way that optimizes our microbiomes for extending our health-span.


Rob Knight is the Director of the Center for Microbiome Innovation at UC San Diego, where he is a Professor of Pediatrics, Bioengineering, and Computer Science & Engineering. He co-founded the Earth Microbiome Project, and The Microsetta Initiative/American Gut Project, which is among the largest crowdfunded science projects of any kind to date. He has spoken at TED, written three books and over 600 scientific articles, and in 2017 he won the Massry Prize, often considered a predictor of the Nobel prize. His work combines microbiology, DNA sequencing, ecology and computer science to understand the vast numbers of microbes that inhabit our bodies and our planet.

Date: December 6

Title: The Future of Immunotherapy:  Treatments benefiting all cancer patients

Time: 10:30–11:30 a.m. followed by the special screening of Flight of the Butterflies at noon.

It’s not an overstatement to say that immunotherapy—an approach that uses our own immune system to kill a tumor—has revolutionized the treatment of cancer. Doctors continue to report incredible results, including tough-to-treat tumors seemingly melting away. However, the treatment doesn’t work for everyone, and even if it does work initially, it often stops working as time goes on.  Jennifer Hope, Ph.D., a postdoctoral researcher in the Bradley lab at Sanford Burnham Prebys, is working to find ways to make cancer immunotherapy work for more people.


Dr. Hope received her PhD in Microbiology and Immunology at Drexel University College of Medicine in Philadelphia, PA. As a postdoctoral fellow in the Bradley lab, her current studies are focused on understanding the cellular and molecular mechanisms involved in preventing or reversing T cell exhaustion in cancer. Ultimately, she hopes these findings can be applied in the development of therapeutics.